Clinical Depression
Learning disabilities, despite normal or high IQ, are common. The risk of dyslexia and
attention-deficient/hyperactivity disorder may also be higher. In addition, psychological problems such as
depression are linked to most sexual disorders.
Treatment
Testosterone: The primary clinical symptoms of KS are treatable. While surgery can correct gynecomastia,
testosterone injections can correct hair loss and promote muscle mass. Testosterone supplementation should begin in
puberty (optimally at age 11 or 12) but is also generic paxil in adulthood. Hormonal screening can assess testosterone
levels performed in the morning. The average male produces 4 to 7 mg of testosterone per day in a circadian pattern
that peaks in the morning and is minimal in the evening. However, testicular size, sterility, and gynecomastia will
not be affected by testosterone supplementation.
Testosterone can be administered as oral, buccal, injectable, and transdermal formulations. IM preparations of
enanthate or cypionate are commonly used (Table 3) and have similar pharmacokinetics and safety profiles. Oral
preparations are infrequently prescribed due to elevations in liver function tests and the risk of hepatotoxicity.
Peak serum levels are achieved in two to five days and return to baseline drug amitriptyline two weeks after injection.
The typical dose is 200 mg every two weeks. If initiated during puberty, the dose is lowered to 50 to 100 mg every
four weeks, then every two weeks until adulthood. Transdermal testosterone may not be an optimal option due to the
scrotal surface area. It is also a more expensive formulation and is not well studied in patients younger zoloft ocd 18
years.
